国际共识聚焦更新：重症成人β-内酰胺类抗生素延长输注推荐获多学会认可
Focused Update to International Consensus Recommendations for the Use of Prolonged-Infusion Beta-Lactam Antibiotics Among Severely Ill Adult Patients: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Care Medicine, and Society of Infectious Diseases Pharmacists.
国际延长输注β-内酰胺类共识小组发布聚焦更新，基于28项RCT的荟萃分析显示延长输注较短期输注降低重症成人死亡风险（RR 0.91，95%CI 0.85-0.97），21项RCT显示临床治愈改善（RR 1.11，95%CI 1.06-1.17）。证据确定性由极低提升至死亡率中等、临床治愈低，并建议持续输注前使用负荷剂量。该更新获美国临床药学会、英国抗菌化疗学会等七家学会认可。
研判指引
延长输注β-内酰胺类共识更新强化重症给药方案，提示大输液企业关注重症科室输注器具与配液需求变化。
来源：Europe PMC｜静脉治疗指南与共识 · pubmed.ncbi.nlm.nih.gov